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84485-00-7 Natural Health Weight Loss Powder Sibutramine Steroids For Pharmaceutical

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84485-00-7 Natural Health Weight Loss Powder Sibutramine Steroids For Pharmaceutical

China 84485-00-7 Natural Health Weight Loss Powder Sibutramine Steroids For Pharmaceutical supplier

Large Image :  84485-00-7 Natural Health Weight Loss Powder Sibutramine Steroids For Pharmaceutical

Product Details:

Place of Origin: China
Brand Name: RX
Certification: ISO,GMP
Model Number: 584

Payment & Shipping Terms:

Minimum Order Quantity: 10grams
Price: negotable
Packaging Details: package in foil bag or as your referecnce
Delivery Time: within 2 days after your payment
Payment Terms: T/T, Western Union, MoneyGram,bank transfer and Bitcoin
Supply Ability: 1000kg/month
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Detailed Product Description
Name: Sibutramine Other Name: Sibutramine Hydfgrochloride
Purity: 99% COA: 84485-00-7
MF: C17H27Cl2N Appearance: White Powder

Weight Loss Powder 99% 84485-00-7 Natural Health Fat Loss Powder Sibutramine Steroids For Pharmaceutical
 
1. Quick Detail:
Sibutramine Hydrochloride
Alias: Reductil
CAS No: 84485-00-7
MF: C17H27Cl2N
MW: 316.31
Purity: 99%
Appearance: White powder, soluble in methanol.

 

Product Name Sibutramine Hydrochloride
Synonyms Sibutramine Hcl; Sibutramine・HCL; MERIDIA
Molecular Formula C17H26ClN
Molecular Weight 279.848
CAS Registry Number 84485-00-7
Molecular Structure  
Density 1.026g/cm3
Boiling point 348.119°C at 760 mmHg
Refractive index 1.527
Flash point 164.337°C
Vapour Pressure 0mmHg at 25°C

 
Sibutramine (usually in the form of the hydrochloride monohydrate salt) is an oral anorexiant. Until 2010 it was marketed and prescribed as an adjunct in the treatment of exogenous obesity along with diet and exercise.
2. Applications:
Medicine reducing weight and antidepressants.
Sibutramine is well absorbed from the GI tract (77%), but undergoes considerable first-pass metabolism, reducing its bioavailability. The drug itself reaches its peak plasma level after 1 hour and has also a half-life of 1 hour. Sibutramine is metabolized by cytochrome P450 isozyme CYP3A4 into two pharmacologically-active primary and secondary amines (called active metabolites 1 and 2) with half-lives of 14 and 16 hours, respectively. Peak plasma concentrations of active metabolites 1 and 2 are reached after three to four hours. The following metabolic pathway mainly results in two inactive conjugated and hydroxylated metabolites (called metabolites 5 and 6). Metabolites 5 and 6 are mainly excreted in the urine.

3. Specifications:
 

Items Standard Results
Description White to kind of white powder kind of white powder
Melting point 193.0-200 196.0-198.9
Water 5-6.5% 5.6%
Solubility Soluble in methanol Complies
PH 4.0-6.0 5
Heavy Metals ≤10ppm Complies
Assay ≥96% 96.21%
Residue on ignition ≤0.1% 0.03%
Single impurity ≤0.2% 0.19%
Conclusion Up to the Standard USP 32.

Contact Details
HONGKONG RONGXIN BIO-TECH CO.,LTD

Contact Person: Manager

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