Tamoxifen Citrate, Nolvadex
CAS NO.:10540-29-1
Purity: 99.5%
Molecular Formula: C26H29NO
Molecular Weight: 371.51
Standard:USP
Assay:99.0-101.0%
White crystalline powder .
Usage:Breast cancer and oophoroma.
Packing: 25kgs drum/ aluminium tin or as required.
Min. order quantity: 10g
Shipment: EMS, DHL, FedEx, TNT
Delivery: safe & timely, around 7days after payment.
Quick Detail:
Product Description:
Nolvadex (tamoxifen citrate) is very comparable to Clomid, behaves in the same manner in all tissues, and is a mixed estrogen agonist/antagonist of the same type as Clomid. The two molecules are also very similar in structure. It is not correct that Nolvadex reduces levels of estrogen: Rather, it blocks estrogen from estrogen receptors and, in those tissues where it is an antagonist, causes the receptor to do nothing.
The claim that Nolvadex reduces gains should not be taken too seriously. The fact is that any number of bodybuilders have made excellent gains while using Nolvadex.
Thus, Dan Duchaine reported that it reduces IGF-1 and therefore reduces gains. However, if this effect exists at all, it must be very minor, due to the excellent gains that many have made, and from the fact that no one has noticed any such thing from Clomid, which has the same activity profile.
However, I would not be surprised if one were to tell a steroid user that Clomid reduced his gains, he would immediately become afraid that Clomid reduced his gains (please note that no one I have ever heard of has noticed this.) Not having been so misled, however, he would not conclude this from his results. But if an authority publishes that such an effect occurs, whether it does or not it can become self-fulfilling by biasing the user.The fact that Nolvadex will reduce water retention may result in the user agreeing that gains are less, since weight gain is less, thus reinforcing the bias.The belief that it reduces gains seems to stem from the fact that the scientific literature reports a slight reduction (individuals using anabolic steroids were not studied though) from use of Nolvadex.
What is Tamoxifen citrate?
Tamoxifen Citrate is a potent and selective inhibitor of PKC (protein kinase C). It is known that Tamoxifen Citrate functions in PKC εtranslocation. Studies suggest that Tamoxifen Citrate functions as an estrogen receptor antagonist in breast tissue. Once bound to the estrogen receptor Tamoxifen Citrate will not allow any other ligand to bind to the receptor. In contrast, Tamoxifen Citrate is an agonist towards this receptor in tissues of the endometrium. Studies indicate Tamoxifen Citrate inhibits DNA synthesis and transcription by recruiting co-repressors, which stop estrogen from interacting with genes. When combined with PAX2, Tamoxifen Citrate can inhibit the proliferation of ERBB2. It is also a high affinity activator of the GPR30 receptor. Tamoxifen Citrate is an activator of Estrogen Receptor.
Tamoxifen is an anticancer drug, is given to treat breast cancer.
Tamoxifen citrate is an anticancer drug, is given to treat breast cancer. It also has proved effective when cancer has spread to other parts of the body. Tamoxifen citrate is most effective in stopping the kind of breast cancer that thrives on estrogen.
Tamoxifen citrateis also prescribed to reduce the risk of invasive breast cancer following surgery and radiation therapy for ductal carcinoma in situ. The drug can also be used to reduce the odds of breast cancer in women at high risk of developing the disease. It does not completely eliminate your chances, but in a five-year study of over 1,500 high-risk women, it slashed the number of cases by 44 percent.
Most important fact about Tamoxifen citrate
Although Tamoxifen citrate reduces the risk of breast cancer, it increases the possibility of developing endometrial (uterine) cancer. Women taking Tamoxifen citrate should have routine gynecological examinations and report any abnormal vaginal bleeding, changes in menstrual periods, change in vaginal discharge, or pelvic pain or pressure to the doctor immediately. Even after Tamoxifen citratetherapy has stopped, any abnormal vaginal bleeding should be reported at once.
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