Triiodothyronine CAS 5817-39-0 Cytomel Reverse T3 Thyroid Hormone
|Product name :||Triiodothyronine,REVERSE T3|
|Synonyms:||Triiodothyronine,reverse;TRIIODOTHYRONINE;REVERSE T3;T3;LIOTHYRONIN;L-3,3',5'-TRIIODOTHYRONINE;(3,5,3')-TRIIODO-L-THYRONINE;Reverse T3|
|Appearance:||White or light yellow powder, almost tasteless.|
|Express:||EMS, DHL, FedEx, etc(door-to-door)|
What is T3 ?
Also known as T3, liothyronine plays an important role in the chemical makeup that controls almost every physiological process in the body, including growth, metabolism, and physical development. T3 hormone also plays a vital function in bone growth and development as well as in the production of chemicals in the central nervous system called neurotransmitters. In addition, T3 has a direct effect on embryonic and fetal growth. As a powerful hormone, T3 acts on the body to boost basal metabolic rate, protein synthesis and sensitivity to catecholamines. It promotes proper growth and maturation of all body cells by regulating carbohydrate, protein, and fat metabolism, which in turn affects how cells use energy.
T3 (liothyronine) improves your body’s energy and oxygen utilization, which is important to preserve life. Liothyronine is a powerful thyroid hormone that is necessary for functioning of almost every major organ in the body except the spleen and the testes. In contrast, T4 or thyroxine hormone, is much less active, and has to be converted to T3 when the body needs it.
T3 and T4 :
The full name of T3 is triiodothyronine, and T4's full name is tetraiodothyronine or thyroxine. T3 and T4 control your body's metabolism. If you don't have enough of them, then your metabolism slows down. Your metabolic rate dictates how quickly you process food, how fast your heart beats, how much heat your body creates-and even how quickly you can think. In essence, T3 and T4 are in charge of how your body uses energy.
T3 and T4 are not equal in strength; T3 is the more active hormone of the two. While T3 is stronger, taking synthetic T4 hormone is considered the standard treatment for hypothyroidism. The reason for this is because most of the T3 in our bodies actually used to be T4. When T4 hormones come into contact with other cells in the bloodstream, they give up an iodine atom to interact with those cells. When T4 loses an iodine atom, it becomes T3.
When this T4 into T3 conversion occurs, T3 then conveys the metabolic "message" to the other cells throughout the body. The benefit of taking only T4 therapy is that you're allowing your body to perform some of the actions it is meant to do, which is taking T4 and changing it into T3. The half life of T4 is also longer compared to T3 (7 days versus 24 hours), that means that it will stay for a longer time in your body after ingestion.
Application of T3:
It affects almost every physiological process in the body, including growth and development, metabolism, body temperature, and heart rate.T3 increases the basalmetabolic rate and, thus, increases the body's oxygen and energy consumption.
1) Effects on Fat Metabolism:
T3 (or more specifically, thyroid hormones in general) are investigated for their interactions with fat mass since, in survey research, thyroid activity may be related to fat mass and BMI.
Some studies suggest a correlation whereas other suggest it does not exist for those with normal thyroid function.It is a contest field, as some studies do exist that suggest a relation even in those with normal thyroid function. These discrepancies may be due to the highly variable 'normal range' of thyroid hormones.
2) Effects on Muscle Tissue:
In obese subjects, a reduction in urinary nitrogen has been reported with T3 supplementation, and was additive to fasting's reduction in urinary nitrogen; suggesting a muscle preserving effect. These results have been replicated a short-term metabolic ward study at 100mcg daily, in four divided dosages.
However, at least one study has noted an increase in urinary nitrogen after four weeks usage, in doses ranging from 0.36-1.01mcg/kg bodyweight.
3) Effects on Cognition:
Thyroid hormone status is correlated with cognition, and a lower level of thyroid hormones is related to depressive-like symptoms.
T3 Dosage :
T3 does speed fat loss. As a guideline, for most 12.5 mcg/day is a conservative "supplement" sort of dosing that seems to have no detectable adverse effect on thyroid function at all.
25 mcg/day is a "supplement" sort of dosing that does have some inhibitory effect.
50 mcg/day is a reasonably conservative bb'ing sort of dose that, of course, is more inhibitory.
75 mcg/day is getting into more of a problem area;
100 mcg/day in many cases leads to loss of muscle size and strength.
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