Exemestane Aromasin Cas 107868-30-4 Anti Estrogen Steroid Cancer Treatment
10grams
MOQ
wholesale prices,negotiable
Price
Exemestane Aromasin Cas 107868-30-4 Anti Estrogen Steroid Cancer Treatment
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Features
Basic Infomation
Place of Origin: Zhejiang,China
Brand Name: Pharma Grade
Certification: ISO,GMP
Model Number: 107868-30-4
High Light:

107868-30-4 Exemestane Aromasin

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Anti Estroge Exemestane Aromasin

Payment & Shipping Terms
Packaging Details: Foil bag or other discreelty package,according the order quantity and different country.
Delivery Time: 1000kg/month
Payment Terms: Western Union, MoneyGram, T/T,bank transfer,Bitocin
Specifications
Name: Exemestane
Other Name: Aromasin
Quality: 99.5%
Apperance: White Or White Crystalline Powder
Usage: Muscle To Reduce Fat
MOQ: 10G
Product Description

Exemestane Aromasin Cas 107868-30-4 Anti Estrogen Steroid Cancer Treatment

 

Exemestane Details


Product name: Exemestan,Aromasin
Chemical Name: 6-Methylenandrosta-1,4-diene-3,17-dione
CAS: 107868-30-4
Molecular Formula: C20H24O2
Molecular Weight: 296.40
MP:193°C
Grade: Medicine grade
Appearance: White to almost white powder
Assay: 99.5% min

 

Exemestane Description


Exemestane is known as a hormonal breast cancer treatment.
Some breast cancers need the hormone oestrogen to grow. In women who have been through the menopause, the main source of oestrogen is through the change of sex hormones called androgens into oestrogen. An enzyme called 'aromatase' is needed for this change to occur. Exemestane works by inhibiting (or blocking) this enzyme. This reduces the amount of oestrogen in your body, which slows the growth of the cancer cells.

 

Fuction of Exemestane


1) Exemestane for breast cancer prevention:
Chemoprevention of breast cancer is an effective strategy to reduce the incidence of this disease in women at risk. The first agents to show a significant chemopreventive effect were the SERMs tamoxifen and raloxifen. An updated comprehensive analysis of all SERM prevention trials showed that they are able to reduce the incidence of breast cancer in high- and average-risk women, an effect that is sustained by a reduction in ER-positive invasive breast cancer

2) Exemestane is a third-generation irreversible steroidal inactivator of the aromatase enzyme and is effective in all the treatment settings for breast cancer, including chemoprevention.
In the metastatic setting, exemestane has been extensively investigated as the first-line, second-line, and further-line treatment and is now registered for the treatment of postmenopausal women with advanced hormone-receptor-positive breast cancer whose disease has progressed following antiestrogen therapy. Of note, the potential lack of cross-resistance with NSAIs yields additional opportunities in the treatment sequence of endocrine agents. Furthermore, based on clinically meaningful results, exemestane with everolimus represents an effective therapeutic option for a disease that has progressed after exposure to NSAIs.
Exemestane is generally well tolerated, with a side effect profile similar to that of other AIs and including menopausal symptoms, arthralgia, bone loss, and altered lipid metabolism.

Exemestane COA

 

TEST ITEMS SPECIFICATION RESULTS
Description White Crystalline Powder White Powder
Identification Positive Positive
Assay(by HPLC) 98.0~102.0% 99.64%
Absorbance(E1cm) 465~495 482.5
Melting Point 191~195℃ 193.5~195.0℃
Loss On Drying 0.5%max 0.19%
Specific Rotation +288°~ +298° +290.2°
Residue On Ignition 0.1%max 0.03%
Related Substances Total:1.5%max <1.3%
Residue Solvents 0.2%max 0.10%
Heavy Metals 20PPm max <10PPm
Conclusion The specification conform with USP35

 

Exemestane Aromasin Cas 107868-30-4 Anti Estrogen Steroid Cancer Treatment 0

 

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1. Guarantee Quality The quality is up to USP standard. We own several sets of analyzing instruments with high efficiency and high sensitivity, such as HPLC,GC and UV spectrophotometer to analyze and control the products. Our company has gotten the approval of ISO9001, and has a complete Q.A. & Q.C.system.

 

2. Guarantee Delivery We cooperate with mature transportation companies and have a variety of transportation channels, such as FedEx, USPS, DHL and so on. It is worth mentioning that we have local warehouses in the United States, Canada and Europe, it ensure that safety delivery of goods.

 

3. Excellent Service From inquiry, order to after-sales service, we provide one-to-one service, and answer any questions for you. And we will track the package after you order, remind you to sign when it arrives until you receive.

 

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