ACE-031 1mg ACVR2B Peptides Hormones Bodybuilding Supplements To Inhibit Myostatin
ACE-031, also referred to as ACVR2B or ActRIIB-IgG1, is a synthetically produced protein that was originally developed by two bio-pharmaceutical companies, namely Acceleron and Shire, for its potential ability to inhibit myostatin and other naturally occurring proteins that limit muscle growth.
It was hypothesized that ACE-031 would act as a decoy receptor for the catabolic proteins, specifically myostatin, and bind to them in an effort to keep them away from muscle fibers. Numerous studies have been conducted to determine if ACE-031 is an effective treatment for children who have Duchenne Muscular Dystrophy (DMD).
ACE-031 Applications:
ACE-031 acts by binding to proteins that normally signal through a particular activin receptor called ActRIIB. Myostatin and other related proteins signal through this receptor to limit muscle growth. When ACE-031 binds to these proteins, it prevents them from interacting with the ActRIIB receptor, thus allowing muscle to grow.
The critical difference between ACE-031 and antibodies to myostatin is that ACE-031 inhibits multiple regulators of muscle mass in addition to myostatin. In preclinical studies, the end result is a greater increase in muscle mass than can be achieved by blocking myostatin alone. In Duchenne, the goal is to offset the loss of muscle due to the lack of dystrophin by increasing the production of new muscle.
What is Myostatin and Why Stop It?
Myostatin, abbreviated GDF-8 (Growth Differentiation Factor-8), is a protein naturally produced in mammals, which acts on muscle cells as an inhibitor of myogenesis (differentiation and growth of muscle cells). The gene encoding myostatin was discovered in 1997 by geneticists Se-Jin Lee and Alexandra McPherron who produced a strain of mutant mice that lack the gene. These scientists produced a strain of mice that lacked the gene and had approximately twice as much muscle as normal mice.
Simple simple simple version: Myostatin tells muscle cells to not grow and not to replicate. Blocking myostatin will help muscles get bigger, to date there has been only Follistatin that is widely used to block myostatin.
China Kungfu Steroid Reliable Supplier
We provide anabolic steroid powder, semi-finished oil, finished products of steroids, Hgh human growth hormone, hcg human chorionic gonadotropin, peptides and sarms powder with high quality.
Why choose us?
1. Guarantee Quality The quality is up to USP standard. We own several sets of analyzing instruments with high efficiency and high sensitivity, such as HPLC,GC and UV spectrophotometer to analyze and control the products. Our company has gotten the approval of ISO9001, and has a complete Q.A. & Q.C.system.
2. Guarantee Delivery We cooperate with mature transportation companies and have a variety of transportation channels, such as FedEx, USPS, DHL and so on. It is worth mentioning that we have local warehouses in the United States, Canada and Europe, it ensure that safety delivery of goods.
3. Excellent Service From inquiry, order to after-sales service, we provide one-to-one service, and answer any questions for you. And we will track the package after you order, remind you to sign when it arrives until you receive.
Welcome to your inquiry. We believe we'll be your trustworthy business partner.
Testosterone Acetate | Trenbolone Acetate | MGF 2mg |
Testosterone Cypionate | Trenbolone Enanthate | PEG MGF 2mg |
Testosterone Decanoate | Boldenone Acetate | CJC-1295 with DAC 2mg |
Testosterone Enanthate | Boldenone undecylenate | CJC-1295withoutDAC 2mg |
Testosterone Isocaproate | Boldenone Cypionate | PT-141 10mg |
Testosterone Phenylpropionate | Boldenone Propionate | MT-1 10mg |
Testosterone Propionate | Nandrolone Decanoate | MT-2 10mg |
Testosterone Undecanoate | Nandrolone phenylpropionate | GHRP-2 5mg |
Mesterone | Nandrolone undecylate | GHRP-6 5mg |
Testosterone Sustanon 250 | Nandrolone cypionate | GHRP-6 10mg |
Clostebol Acetate | Nandrolone propionate | Ipamorelin 2mg |
Methylandrostanolone | Methyltrienolone | Hexarelin 2mg |
Methenolone Enanthate | Drostanolone Propionate | Sermorelin 2mg |
Methenolone Acetate | Drostanolone Enanthate | Oxytocin 2mg |
Anadrol | Stanolone | TB500 2mg |
Anavar | Tadalafil | pentadecapeptide BPC 157 2mg |
Winstrol | Vardenafil | GH 176-191 2mg |
Clomifene citrate | Dianabol | Triptorelin 2mg |
Toremifene citrate | Tamoxifen Citrate | Tesamorelin 2mg |
Finasteride | hydrochloride | Gonadorelin 2mg |
Selank 5mg | DSIP 2mg | Gonadorelin 10mg |